[MrDK]

I have stayed at the Holiday Inn in Silom a number of times, each time has been either for business or I have been checking in with "company". I don't know for sure whether they are guest friendly or not, but many say it is not so take their word for it; or at the least send them an email and ask directly (and specifically). If the email is affirmative save a copy and if possible book for double occupancy.

Other than the guest issue it is a great hotel. Lots of good restaurants around and relatively close to Patpong.

If you have plans to bring guests back to your hotel, it could ruin it if the hotel will not allow you to do so. If you think you may spend most of your time at or near Nana/Soi Cowboy, forget the Holiday Inn and book near your playground.