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I'd follow Gollums advice - choose safemode with networking, you may want first to right click on the TaskBar, select Task Manager, select processes and see if anything is using a lot(most) of CPU or memory and try killing that process.
Once you're fixed get youself a good anti-virus program (I use Avast - it's free!) and some anti-spyware programs like Spybot, Spyware Blaster and Ad-aware (I use all three) and make sure they're updated regularly.
Good luck!
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